What Is Axon Therapy and Who Can It Help?

Living with chronic pain can feel like you’re constantly fighting an uphill battle. Medications may only take the edge off, and traditional treatments don’t always bring lasting relief. If that describes you, you’ll be excited to learn about Axon Therapy mPNS®, a new, breakthrough form of neuromodulation therapy designed to calm pain and promote healing at its source.
If you’ve been searching for a safe, 100% non-invasive option that gives real relief, Axon mPNS is worth exploring.

What Exactly Is Axon Therapy mPNS®?

Axon Therapy mPNS (magnetic Peripheral Nerve Stimulation) is an innovative, FDA-cleared, non-invasive treatment that utilizes magnetic pulses to target the nerves causing pain.[1] By stimulating those nerves, it helps “reset” pain signals so your brain no longer interprets them as overwhelming discomfort.[2]

It’s essential to understand what Axon Therapy is not. Some patients compare it to TENS (transcutaneous electrical nerve stimulation) or even conventional peripheral nerve stimulation. But unlike those:

  • It doesn’t use electrical currents through skin electrodes. Instead, it uses magnetic energy to activate nerves beneath the skin gently [3]
  • It’s non-surgical. Unlike implanted PNS devices, there are no wires or leads placed in your body.
  • It’s pain-free. Patients don’t feel shocks, zaps, or burning sensations during treatment.

Think of Axon Therapy as a next-generation of neuromodulation—gentle, non-invasive, and highly targeted.


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How Does Magnetic Energy Reduce My Pain?

It’s hard to imagine that magnets can relieve pain, but this isn’t the kind that you stick on your fridge. Axon Therapy utilizes powerful yet gentle pulsed magnets to safely stimulate peripheral nerves beneath the skin, causing no discomfort.[4]

Chronic pain often happens because nerves become “hypersensitive,” sending out distress signals long after an injury has healed or even without a clear cause.[5] Axon Therapy delivers short bursts of magnetic energy that stimulate those overactive nerve fibers.

This process:

  • Helps calm abnormal nerve activity [6]
  • Restores healthier communication between nerves and the brain.
  • Leads to lasting pain relief after a short series of treatments [4]
  • Promotes nerve healing and may encourage better circulation

Instead of masking pain, Axon Therapy retrains the nervous system and helps you feel like you’ve taken back control of your life.

Who Is Axon Therapy Best For?

Axon Therapy mPNS® is designed for adults with chronic neuropathic pain, especially when other treatments haven’t been effective.

Conditions shown to respond include:

  • Painful diabetic neuropathy (PDN) (burning, tingling or numbness in feet and legs) [1]
  • Post-surgical nerve pain
  • Complex regional pain syndrome (CRPS)
  • Nerve injuries, pinched nerves or entrapments [7]
  • Postherpetic neuralgia [6]
  • Trigeminal neuralgia [6]
  • Nerve root pain [6]
  • Phantom limb pain [6]
  • Headaches and migraines
  • Frozen shoulder
  • Fibromyalgia
  • Myofascial pain syndrome
  • Post-traumatic musculoskeletal pain

The ideal patient is someone seeking a non-drug, non-surgical option that integrates seamlessly into daily life. Veterans who received Axon Therapy at the VA have found meaningful relief, reporting fewer pain flares, reduced reliance on medication, and an increased ability to stay active.

Why Patients Choose Axon Therapy: The Benefits

Patients often appreciate that this modern neuromodulation, Axon Therapy mPNS®, is:

  • Quick and easy: Sessions typically last about 15 minutes per area treated [3]
  • Pain-free: Most people feel only a light tapping sensation during treatment.
  • Non-invasive: No needles, no implants, no recovery time.
  • Safe and side-effect free: Clinical studies show no significant adverse effects [6]
  • Long-lasting relief: Many patients experience pain reduction that lasts weeks to months after completing a treatment series [2]

Covered by new CPT coding: Having its own procedure code helps clinics bring it to more patients [8]

How Do I Know if Axon Therapy mPNS® Is Right for Me?

Have you been missing out on life because of stubborn nerve pain that medications, injections, or other treatments haven’t relieved? Axon neuromodulation therapy may be the reset button you’ve been waiting for! The only way to know if this treatment is right for you is to talk with your pain management specialist. They’ll review your medical history and determine if your neuropathic pain makes you a good candidate.

Chronic pain can feel like a prison sentence, but with modern options like Axon Therapy, there’s real hope for lasting relief without surgery or side effects.

Disclaimer: This information is provided for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Axon Therapy may not be suitable for everyone, so it’s essential to consult your physician or a pain management specialist to determine if it’s an appropriate option for you.

Resources:

  1. Pharmaceutical Executive Editorial Staff. FDA Clears Neuralace Medical’s Noninvasive Axon Therapy for Painful Diabetic Neuropathy. Pharmaceutical Executive [Internet]. Published January 12, 2024. Accessed September 23, 2025. Available from: https://www.pharmexec.com/view/fda-clears-neuralace-medical-s-noninvasive-axon-therapy-for-painful-diabetic-neuropathy
  2. Kapural L, Patel J, Rosenberg JC, Li S, Amirdelfan K, Bedder M. Safety and Efficacy of Axon Therapy (SEAT Study), Utilizing Magnetic Peripheral Nerve Stimulation (mPNS) for Treatment of Neuropathic Pain. J Pain Res [Internet]. 2024;17:3167-3174. Published 2024 Sep 28. doi:10.2147/JPR.S481944 Accessed September 23, 2025. Available from: https://pmc.ncbi.nlm.nih.gov/articles/PMC11446200/
  3. Axon Therapy. Neuralace Medical [Internet]. Published July 23, 2025. Accessed September 23, 2025. Available from: https://neuralacemedical.com/axon-therapy/
  4. Kapural L, Patel J, Rosenberg J, Li S, Amirdelfan K, Bedder M. Efficacy and Safety of Magnetic Peripheral Nerve Stimulation for Treatment of Neuropathic Pain; One Year Follow Up of Long-Term Outcomes. Journal of Pain Research [Internet]. 2025;Volume 18:4471-4481. doi:https://doi.org/10.2147/jpr.s538263 Accessed September 23, 2025. Available from: https://neuralacemedical.com/wp-content/uploads/2025/09/JPR-538263-efficacy-and-safety-of-magnetic-peripheral-nerve-stimulation.pdf
  5. Bedder M, Parker L. Magnetic Peripheral Nerve Stimulation (mPNS) for Chronic Pain. J Pain Res. 2023;16:2365-2373. Published 2023 Jul 12. doi:10.2147/JPR.S409331 Accessed September 23, 2025. Available from: https://pmc.ncbi.nlm.nih.gov/articles/PMC10350402/
  6. Kapural L, Patel J, Rosenberg JC, Li S, Kasra Amirdelfan, Bedder M. Safety and Efficacy of Axon Therapy (SEAT Study), Utilizing Magnetic Peripheral Nerve Stimulation (mPNS) for Treatment of Neuropathic Pain. Journal of Pain Research [Internet]. 2024;Volume 17:3167-3174. doi:https://doi.org/10.2147/jpr.s481944 Accessed September 23, 2025. Available from: https://www.tandfonline.com/doi/full/10.2147/JPR.S481944#d1e265
  7. Brown L, Gage E, Cordner H, Kapural L, Rosenberg J, Bedder M. Safety and Efficacy of Magnetic Peripheral Nerve Stimulation for Treating Painful Diabetic Neuropathy. Neuromodulation Technology at the Neural Interface. Published online April 1, 2025. doi:https://doi.org/10.1016/j.neurom.2025.03.074 Accessed September 23, 2025. Available from: https://www.neuromodulationjournal.org/article/S1094-7159(25)00138-2/fulltext
  8. Neuralace Medical, Inc. NEURALACE MEDICAL ANNOUNCES THE AMERICAN MEDICAL ASSOCIATION ISSUES UNIQUE CATEGORY III CPT® CODE FOR TRANSCUTANEOUS MAGNETIC NERVE STIMULATION. Pr Newswire [Internet]. Published June 29, 2022. Accessed September 23, 2025. Available from: https://www.prnewswire.com/news-releases/neuralace-medical-announces-the-american-medical-association-issues-unique-category-iii-cpt-code-for-transcutaneous-magnetic-nerve-stimulation-301577587.html
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